Tuesday, November 2, 2010

Vitamin D.

Vitamin D

Vitamin D has been a necessary vitamin since the beginning - 90% of vitamin D is derived from solar ultraviolet-B (UVB) irradiance. Vitamin D helps both to prevent and to treat chronic diseases including many types of cancer, cardiovascular disease (coronary heart disease, stroke, etc.), congestive heart failure, diabetes mellitus (types 1 and 2), osteoporosis, falls, and fractures. It is also effective against infectious diseases including both bacteria and viral infections: bacterial vaginosis, pneumonia, dental caries, periodontal disease, tuberculosis, sepsis/septicemia, Epstein-Barr virus, and influenza type A such as A/H1N1 influenza. The autoimmune diseases include asthma, type 1 diabetes mellitus, multiple sclerosis, and perhaps rheumatoid arthritis. Pregnancy outcomes are also adversely affected by low serum D levels. Studies have shown that with sufficient Vitamin D mortality rates could be reduced by about 15%.

Supplements represent an efficient way to obtain sufficient vitamin D. African-Americans should consider taking 3000 International Units (IU) per day while White-Americans should consider taking 2000 IU/day. The current dietary guideline, approximately 400 IU/day, was based on the amount of vitamin D in a spoonful of cod liver oil, which prevented rickets.

There are few adverse effects of vitamin D. With whole-body exposure to the sun, one can make at least 10,000 IU/day in a short time. Adverse effects such as hypercalcemia have been found in general only for 20,000-40,000 IU/day for very long periods. However, those with certain diseases such as adenoma of the parathyroid gland, granulomatous diseases, lymphoma, sarcoidosis, and tuberculosis, should limit their vitamin D intake or production due to the fact that the body's innate immune system produces too much 1,25-dihydroxyvitamin D in the serum, which can raise serum calcium levels too high.

During pregnancy and lactation, women should be taking about 6000 IU/day. The current US "Adequate Intake" recommendation is a mere 200 IU/day. Bruce W. Hollis and Carol L. Wagner, Medical University of South Carolina, recently completed a randomized controlled trial vitamin D supplementation for pregnant and nursing women and found that even 2000 IU/day was inadequate, and that there were no adverse effects with 6000 IU/day. For the text of a Vitamin D Scientists' Call to Action, please go to http://www.grassrootshealth.net .

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